TEAD4 anticorps (AA 74-434) (HRP)
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- Antigène Voir toutes TEAD4 Anticorps
- TEAD4 (TEA Domain Family Member 4 (TEAD4))
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Épitope
- AA 74-434
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TEAD4 est conjugé à/à la HRP
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Transcriptional enhancer factor TEF-3 protein (74-434AA)
- Isotype
- IgG
- Top Product
- Discover our top product TEAD4 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- TEAD4 (TEA Domain Family Member 4 (TEAD4))
- Autre désignation
- TEAD4 (TEAD4 Produits)
- Synonymes
- anticorps TEAD4, anticorps rtef1, anticorps tef-3, anticorps eftr-2, anticorps tefr-1, anticorps tcf13l1, anticorps hrtef-1b, anticorps xdtef-1, anticorps xlDTEF-1, anticorps RTEF-1, anticorps TEF-1, anticorps TEF-3, anticorps EFTR-2, anticorps RTEF1, anticorps TCF13L1, anticorps TEF3, anticorps TEFR-1, anticorps hRTEF-1B, anticorps ETFR-2, anticorps Etfr2, anticorps FR-19, anticorps TEAD-4, anticorps Tcf13r1, anticorps Tef3, anticorps Tefr, anticorps Tefr1, anticorps Tefr1a, anticorps TEA domain transcription factor 4, anticorps TEA domain transcription factor 4 S homeolog, anticorps TEA domain family member 4, anticorps TEAD4, anticorps tead4, anticorps tead4.S, anticorps Tead4
- Sujet
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Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC \'enhansons\' (5\'-GTGGAATGT-3\') and activates transcription. Binds to the M-CAT motif.
Aliases: EFTR 2 antibody, EFTR2 antibody, hRTEF 1B antibody, hRTEF1B antibody, MGC9014 antibody, OTTHUMP00000238119 antibody, OTTHUMP00000238122 antibody, OTTHUMP00000238124 antibody, Related to TEF 1 antibody, Related to TEF1 antibody, Related transcription enhancer factor 1B antibody, RTEF1 antibody, TCF13L1 antibody, TEA domain family member 4 antibody, TEAD 4 antibody, TEAD-4 antibody, TEAD4 antibody, TEAD4_HUMAN antibody, TEF 3 antibody, TEF3 antibody, TEFR 1 antibody, TEFR1 antibody, Transcription factor 13 (SV40 transcriptional enhancer factor) like 1 antibody, Transcription factor 13 like 1 antibody, Transcription factor 13-like 1 antibody, Transcription factor RTEF 1 antibody, Transcription factor RTEF-1 antibody, Transcription factor RTEF1 antibody, Transcriptional enhancer factor 1 related antibody, Transcriptional enhancer factor 3 antibody, Transcriptional enhancer factor TEF 3 antibody, Transcriptional enhancer factor TEF-3 antibody, Transcriptional enhancer factor TEF3 antibody
- UniProt
- Q15561
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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