ZBTB33 anticorps (AA 113-228) (Biotin)

N° du produit ABIN7172776

Détail du produit anti-ZBTB33 anticorps (Biotin)

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Épitope: AA 113-228

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB33 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Transcriptional regulator Kaiso protein (113-228AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ZBTB33

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Autre désignation: ZBTB33 (ZBTB33 Produits)

Synonymes: anticorps kaiso, anticorps ZNF-kaiso, anticorps ZNF348, anticorps AW260253, anticorps E130014G12Rik, anticorps Kaiso, anticorps Znf-kaiso, anticorps RGD1566309, anticorps zinc finger and BTB domain containing 33 S homeolog, anticorps zinc finger and BTB domain containing 33, anticorps zbtb33.S, anticorps ZBTB33, anticorps Zbtb33

Sujet:

Background: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5\'-CGCG-3\' and also binds to the non-methylated consensus sequence 5\'-CTGCNA-3\' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453).

Aliases: Kaiso antibody, Kaiso protein antibody, Kaiso transcription factor antibody, KAISO_HUMAN antibody, Transcriptional regulator Kaiso antibody, ZBTB 33 antibody, Zbtb33 antibody, Zinc finger and BTB domain containing 33 antibody, Zinc finger and BTB domain-containing protein 33 antibody, Zinc finger transcription factor Kaiso antibody, ZNF 348 antibody, ZNF Kaiso antibody, ZNF348 antibody

UniProt: Q86T24