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LRRC32 anticorps (AA 301-500) (HRP)

LRRC32 Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7172810
  • Antigène Voir toutes LRRC32 Anticorps
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Épitope
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-500
    Reactivité
    • 29
    • 13
    • 9
    • 1
    Humain
    Hôte
    • 19
    • 16
    • 4
    • 1
    Lapin
    Clonalité
    • 20
    • 20
    Polyclonal
    Conjugué
    • 21
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Cet anticorp LRRC32 est conjugé à/à la HRP
    Application
    • 21
    • 16
    • 14
    • 10
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)
    Isotype
    IgG
    Top Product
    Discover our top product LRRC32 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Autre désignation
    LRRC32 (LRRC32 Produits)
    Sujet

    Background: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).

    Aliases: D11S833E antibody, GARP antibody, Garpin antibody, Glycoprotein A repetitions predominant antibody, Leucine rich repeat containing 32 antibody, Leucine-rich repeat-containing protein 32 antibody, LRC32_HUMAN antibody, LRRC32 antibody

    UniProt
    Q14392
    Pathways
    Activated T Cell Proliferation
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