TRPV4 anticorps (AA 1-230)
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- Antigène Voir toutes TRPV4 Anticorps
- TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
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Épitope
- AA 1-230
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TRPV4 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Transient receptor potential cation channel subfamily V member 4 protein (1-230AA)
- Isotype
- IgG
- Top Product
- Discover our top product TRPV4 Anticorps primaire
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
- Autre désignation
- TRPV4 (TRPV4 Produits)
- Synonymes
- anticorps wu:fp52e02, anticorps CMT2C, anticorps HMSN2C, anticorps OTRPC4, anticorps SMAL, anticorps SPSMA, anticorps SSQTL1, anticorps TRP12, anticorps VRL2, anticorps VROAC, anticorps 0610033B08Rik, anticorps Trp12, anticorps VR-OAC, anticorps VRL-2, anticorps Otrpc4, anticorps Vroac, anticorps transient receptor potential cation channel, subfamily V, member 4, anticorps transient receptor potential cation channel subfamily V member 4, anticorps trpv4, anticorps TRPV4, anticorps Trpv4
- Sujet
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Background: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH , citrate and phorbol esters. Increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca2+ in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
Aliases: BCYM3 antibody, CMT2C antibody, HMSN2C antibody, osm 9 like TRP channel 4 antibody, Osm-9-like TRP channel 4 antibody, OSM9 like transient receptor potential channel 4 antibody, Osmosensitive transient receptor potential channel 4 antibody, OTRPC 4 antibody, OTRPC4 antibody, SMAL antibody, SPSMA antibody, SSQTL1 antibody, Transient receptor potential cation channel subfamily V member 4 antibody, Transient receptor potential protein 12 antibody, TRP 12 antibody, TRP12 antibody, TRPV 4 antibody, TrpV4 antibody, TRPV4_HUMAN antibody, Vanilloid receptor like channel 2 antibody, Vanilloid receptor like protein 2 antibody, Vanilloid receptor related osmotically activated channel antibody, Vanilloid receptor-like channel 2 antibody, Vanilloid receptor-like protein 2 antibody, Vanilloid receptor-related osmotically-activated channel antibody, VR 4 antibody, VR OAC antibody, VR-OAC antibody, VR4 antibody, VRL 2 antibody, VRL-2 antibody, VRL2 antibody, VROAC antibody
- UniProt
- Q9HBA0
- Pathways
- Hormone Transport, Cell-Cell Junction Organization
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