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TMEM59 anticorps (AA 59-201) (Biotin)

TMEM59 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7173246
  • Antigène Voir toutes TMEM59 Anticorps
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Épitope
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 59-201
    Reactivité
    • 15
    • 10
    Humain
    Hôte
    • 25
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TMEM59 est conjugé à/à la Biotin
    Application
    • 22
    • 13
    • 13
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Transmembrane protein 59 protein (59-201AA)
    Isotype
    IgG
    Top Product
    Discover our top product TMEM59 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Autre désignation
    TMEM59 (TMEM59 Produits)
    Synonymes
    anticorps Tmem59, anticorps C1orf8, anticorps HSPC001, anticorps 1110001M20Rik, anticorps 3110046P06Rik, anticorps AI256529, anticorps D4Ertd20e, anticorps MTDCF1, anticorps ORF18, anticorps transmembrane protein 59, anticorps tmem59, anticorps Tmem59, anticorps TMEM59
    Sujet

    Background: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy (PubMed:27273576, PubMed:23376921). Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP (PubMed:20427278). Inhibits APP transport to the cell surface and further shedding (PubMed:20427278).

    Aliases: C1orf8 antibody, HSPC001 antibody, Liver membrane-bound protein antibody, TMEM59 antibody, TMEM59 transmembrane protein 59 antibody, TMM59_HUMAN antibody, Transmembrane protein 59 antibody

    UniProt
    Q9BXS4
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