TMEM59 anticorps (AA 59-201) (Biotin)
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- Antigène Voir toutes TMEM59 Anticorps
- TMEM59 (Transmembrane Protein 59 (TMEM59))
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Épitope
- AA 59-201
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TMEM59 est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Transmembrane protein 59 protein (59-201AA)
- Isotype
- IgG
- Top Product
- Discover our top product TMEM59 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- TMEM59 (Transmembrane Protein 59 (TMEM59))
- Autre désignation
- TMEM59 (TMEM59 Produits)
- Synonymes
- anticorps Tmem59, anticorps C1orf8, anticorps HSPC001, anticorps 1110001M20Rik, anticorps 3110046P06Rik, anticorps AI256529, anticorps D4Ertd20e, anticorps MTDCF1, anticorps ORF18, anticorps transmembrane protein 59, anticorps tmem59, anticorps Tmem59, anticorps TMEM59
- Sujet
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Background: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy (PubMed:27273576, PubMed:23376921). Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP (PubMed:20427278). Inhibits APP transport to the cell surface and further shedding (PubMed:20427278).
Aliases: C1orf8 antibody, HSPC001 antibody, Liver membrane-bound protein antibody, TMEM59 antibody, TMEM59 transmembrane protein 59 antibody, TMM59_HUMAN antibody, Transmembrane protein 59 antibody
- UniProt
- Q9BXS4
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