SIRPA anticorps (AA 31-373)

N° du produit ABIN7174125

Détail du produit anti-SIRPA anticorps

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Épitope: AA 31-373

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRPA est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Tyrosine-protein phosphatase non-receptor type substrate 1 protein (31-373AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: SIRPA (SIRPA Produits)

Synonymes: anticorps BIT, anticorps CD172A, anticorps MFR, anticorps MYD-1, anticorps P84, anticorps PTPNS1, anticorps SHPS1, anticorps SIRP, anticorps SIRPA, anticorps SIRP-A1, anticorps SIRP-B1, anticorps AI835480, anticorps Bit, anticorps CD172a, anticorps Ptpns1, anticorps SHP-1, anticorps SHPS-1, anticorps swc3, anticorps signal regulatory protein alpha, anticorps myeloperoxidase, anticorps signal-regulatory protein alpha, anticorps tyrosine-protein phosphatase non-receptor type substrate 1, anticorps SIRPA, anticorps MPO, anticorps LOC458039, anticorps LOC100400378, anticorps LOC100590224, anticorps Sirpa

Sujet:

Background: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.

Aliases: Signal regulatory protein alpha type 1 antibody, Bit antibody, Brain Ig like molecule with tyrosine based activation motifs antibody, Brain Ig-like molecule with tyrosine-based activation motifs antibody, Brain immunoglobulin like molecule with tyrosine based activation motifs antibody, CD172 antigen like family member A antibody, CD172 antigen-like family member A antibody, CD172a antibody, CD172a antigen antibody, Inhibitory receptor SHPS-1 antibody, Macrophage fusion receptor antibody, MFR antibody, MYD 1 antibody, Myd 1 antigen antibody, MyD-1 antigen antibody, p84 antibody, Protein tyrosine phosphatase non receptor type substrate 1 antibody, PTPNS1 antibody, SHP substrate 1 antibody, SHPS-1 antibody, SHPS1 antibody, SHPS1_HUMAN antibody, Signal regulatory protein alpha 2 antibody, Signal regulatory protein alpha 3 antibody, Signal regulatory protein alpha antibody, Signal regulatory protein alpha type 2 antibody, Signal-regulatory protein alpha-1 antibody, Signal-regulatory protein alpha-2 antibody, Signal-regulatory protein alpha-3 antibody, SIRP antibody, Sirp-alpha-1 antibody, Sirp-alpha-2 antibody, Sirp-alpha-3 antibody, SIRPA antibody, SIRPalpha antibody, SIRPalpha1 antibody, SIRPalpha2 antibody, SIRPalpha3 antibody, Tyrosine phosphatase SHP substrate 1 antibody, Tyrosine protein phosphatase non receptor type substrate 1 antibody, Tyrosine-protein phosphatase non-receptor type substrate 1 antibody

UniProt: P78324