LSM6 anticorps (AA 1-80)

N° du produit ABIN7174196

Détail du produit anti-LSM6 anticorps

Antigène: LSM6 (LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6))

Épitope: AA 1-80

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LSM6 est non-conjugé

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human U6 snRNA-associated Sm-like protein LSm6 protein (1-80AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LSM6

Antigène: LSM6 (LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6))

Autre désignation: LSM6 (LSM6 Produits)

Synonymes: anticorps zgc:92379, anticorps YDR378C, anticorps 1500031N17Rik, anticorps 2410088K19Rik, anticorps AI747288, anticorps RGD1561937, anticorps LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated S homeolog, anticorps LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated, anticorps lsm6.S, anticorps lsm6, anticorps LSM6, anticorps Lsm6

Sujet:

Background: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5\'-to-3\' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3\'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).

Aliases: LSM6U6 snRNA-associated Sm-like protein LSm6 antibody

UniProt: P62312