USP14 anticorps (C-Term) (HRP)

N° du produit ABIN7174261

Détail du produit anti-USP14 anticorps (HRP)

Antigène: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Épitope: AA 1-494, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP14 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14 protein (1-494AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur USP14

Antigène: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Autre désignation: USP14 (USP14 Produits)

Synonymes: anticorps TGT, anticorps DDBDRAFT_0202821, anticorps DDBDRAFT_0237695, anticorps DDB_0202821, anticorps DDB_0237695, anticorps 2610005K12Rik, anticorps 2610037B11Rik, anticorps AW107924, anticorps C78769, anticorps ax, anticorps zgc:55949, anticorps wu:fk63d09, anticorps MGC81945, anticorps tgt, anticorps MGC69343, anticorps USP14, anticorps ubiquitin specific peptidase 14, anticorps peptidase C19 family protein, anticorps ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase), anticorps ubiquitin specific protease 14, anticorps ubiquitin specific peptidase 14 S homeolog, anticorps universal stress protein, anticorps Ubiquitin carboxyl-terminal hydrolase 14, anticorps USP14, anticorps usp14, anticorps Usp14, anticorps Bm1_28765, anticorps usp14.S, anticorps RR_RS06480, anticorps usp-14

Sujet:

Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Aliases: Deubiquitinating enzyme 14 antibody, TGT antibody, tRNA guanine transglycosylase 60 kD subunit antibody, tRNA guanine transglycosylase antibody, Ubiquitin carboxyl terminal hydrolase 14 antibody, Ubiquitin carboxyl-terminal hydrolase 14 antibody, Ubiquitin specific peptidase 14 antibody, Ubiquitin specific processing protease 14 antibody, Ubiquitin specific protease 14 antibody, Ubiquitin thiolesterase 14 antibody, Ubiquitin-specific-processing protease 14 antibody, UBP14_HUMAN antibody, USP 14 antibody, USP14 antibody

UniProt: P54578