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USP37 anticorps (AA 671-797) (FITC)

USP37 Reactivité: Humain Hôte: Lapin Polyclonal FITC
N° du produit ABIN7174326
  • Antigène Voir toutes USP37 Anticorps
    USP37 (Ubiquitin Specific Peptidase 37 (USP37))
    Épitope
    • 8
    • 8
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 671-797
    Reactivité
    • 36
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 36
    Lapin
    Clonalité
    • 36
    Polyclonal
    Conjugué
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    Cet anticorp USP37 est conjugé à/à la FITC
    Application
    Veuillez nous consulter SVP
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 37 protein (671-797AA)
    Isotype
    IgG
    Top Product
    Discover our top product USP37 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    USP37 (Ubiquitin Specific Peptidase 37 (USP37))
    Autre désignation
    USP37 (USP37 Produits)
    Synonymes
    anticorps 4932415L06Rik, anticorps C330008N13Rik, anticorps wu:fi15b04, anticorps wu:fi38d03, anticorps zgc:152882, anticorps zgc:153999, anticorps ubiquitin specific peptidase 37, anticorps USP37, anticorps usp37, anticorps Usp37
    Sujet

    Background: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of \'Lys-11\'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of \'Lys-48\'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).

    Aliases: Deubiquitinating enzyme 3 antibody, Deubiquitinating enzyme 37 antibody, EC 3.1.2.15 antibody, KIAA1594 antibody, MGC117261 antibody, OTTHUMP00000164146 antibody, tmp_locus_50 antibody, Ubiquitin carboxyl-terminal hydrolase 37 antibody, Ubiquitin specific peptidase 37 antibody, Ubiquitin specific processing protease 37 antibody, Ubiquitin specific protease 37 antibody, Ubiquitin thioesterase 37 antibody, Ubiquitin thiolesterase 37 antibody, Ubiquitin-specific-processing protease 37 antibody, UBP37_HUMAN antibody, USP37 antibody

    UniProt
    Q86T82
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