USP5 anticorps (C-Term) (Biotin)

N° du produit ABIN7174349

Détail du produit anti-USP5 anticorps (Biotin)

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Épitope: AA 201-500, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP5 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 5 protein (201-500AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur USP5

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Autre désignation: USP5 (USP5 Produits)

Synonymes: anticorps ISOT, anticorps AA407472, anticorps ISOT-1, anticorps Ucht, anticorps ubiquitin specific peptidase 5, anticorps ubiquitin carboxyl-terminal hydrolase 5, anticorps ubiquitin carboxyl-terminal hydrolase 5, putative, anticorps ubiquitin specific protease 5, anticorps ubiquitin specific peptidase 5 (isopeptidase T), anticorps USP5, anticorps CNH02890, anticorps EHI_049940, anticorps CC1G_12961, anticorps MCYG_01862, anticorps CGB_L3600C, anticorps PY00546, anticorps Usp5

Sujet:

Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored \'Lys-48\'-linked polyubiquitin disassembly. Binds linear and \'Lys-63\'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Aliases: Deubiquitinating enzyme 5 antibody, Isopeptidase T antibody, ISOT 1 antibody, ISOT antibody, Ubiquitin carboxyl-terminal hydrolase 5 antibody, Ubiquitin isopeptidase T antibody, Ubiquitin specific peptidase 5 (isopeptidase T) antibody, Ubiquitin specific peptidase 5 antibody, Ubiquitin specific processing protease 5 antibody, Ubiquitin specific protease 5 (isopeptidase T) antibody, Ubiquitin specific protease 5 (ubiquitin isopeptidase T) antibody, Ubiquitin thioesterase 5 antibody, Ubiquitin thiolesterase 5 antibody, Ubiquitin-specific-processing protease 5 antibody, UBP5_HUMAN antibody, Usp5 antibody

UniProt: P45974