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USP8 anticorps (C-Term)

USP8 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7174360
  • Antigène Voir toutes USP8 Anticorps
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Épitope
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-270, C-Term
    Reactivité
    • 35
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 32
    • 2
    • 1
    Lapin
    Clonalité
    • 33
    • 2
    Polyclonal
    Conjugué
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp USP8 est non-conjugé
    Application
    • 31
    • 14
    • 12
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 8 protein (1-270AA)
    Isotype
    IgG
    Top Product
    Discover our top product USP8 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Autre désignation
    USP8 (USP8 Produits)
    Synonymes
    anticorps HumORF8, anticorps UBPY, anticorps AI574262, anticorps AW557536, anticorps Ubpy, anticorps mKIAA0055, anticorps ubiquitin carboxyl-terminal hydrolase 8, anticorps ubiquitin specific peptidase 8, anticorps LOC9310109, anticorps MGYG_00369, anticorps USP8, anticorps Usp8
    Sujet

    Background: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both \\\'Lys-48\\\' an \\\'Lys-63\\\'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.

    Aliases: Deubiquitinating enzyme 8 antibody, FLJ34456 antibody, hUBPy antibody, HumORF8 antibody, KIAA0055 antibody, MGC129718 antibody, SPG59 antibody, Ubiquitin carboxyl-terminal hydrolase 8 antibody, Ubiquitin isopeptidase Y antibody, ubiquitin specific peptidase 8 antibody, Ubiquitin thioesterase 8 antibody, Ubiquitin-specific-processing protease 8 antibody, UBP8_HUMAN antibody, UBPY antibody, Usp8 antibody

    UniProt
    P40818
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