UBASH3A anticorps (AA 287-455)

N° du produit ABIN7174413

Détail du produit anti-UBASH3A anticorps

Antigène: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Épitope: AA 287-455

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBASH3A est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ubiquitin-associated and SH3 domain-containing protein A protein (287-455AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur UBASH3A

Antigène: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Autre désignation: UBASH3A (UBASH3A Produits)

Synonymes: anticorps UBASH3A, anticorps CLIP4, anticorps STS-2, anticorps TULA, anticorps TULA-1, anticorps 5830413C03Rik, anticorps C330001M22, anticorps Sts-2, anticorps ubiquitin associated and SH3 domain containing A, anticorps ubiquitin associated and SH3 domain containing, A, anticorps UBASH3A, anticorps Ubash3a

Sujet:

Background: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH . May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.

Aliases: Cbl interacting protein 4 antibody, Cbl-interacting protein 4 antibody, CLIP4 antibody, STS 2 antibody, STS-2 antibody, Suppressor of T cell receptor signaling 2 antibody, Suppressor of T-cell receptor signaling 2 antibody, T cell ubiquitin ligand antibody, T cell ubiquitin ligand protein antibody, T-cell ubiquitin ligand 1 antibody, TULA antibody, TULA-1 antibody, UBASH3A antibody, ubiquitin associated and SH3 domain containing, A antibody, Ubiquitin-associated and SH3 domain-containing protein A antibody, UBS3A_HUMAN antibody

UniProt: P57075