UBE2S anticorps (AA 1-222)

N° du produit ABIN7174484

Détail du produit anti-UBE2S anticorps

Antigène: UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))

Épitope: AA 1-222

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2S est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ubiquitin-conjugating enzyme E2 S protein (1-222AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur UBE2S

Antigène: UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))

Autre désignation: UBE2S (UBE2S Produits)

Synonymes: anticorps E2-EPF, anticorps E2EPF, anticorps EPF5, anticorps 0910001J09Rik, anticorps 6720465F12Rik, anticorps AA409170, anticorps RGD1564746, anticorps ube2s, anticorps UBE2S, anticorps DDBDRAFT_0188215, anticorps DDBDRAFT_0305006, anticorps DDB_0188215, anticorps DDB_0305006, anticorps e2-epf, anticorps e2epf, anticorps epf5, anticorps ube2s.1, anticorps ube2s.1-b, anticorps ube2s.1-a, anticorps ubiquitin conjugating enzyme E2 S, anticorps ubiquitin-conjugating enzyme E2S, anticorps ubiquitin-conjugating enzyme e2S, putative, anticorps ubiquitin-conjugating enzyme E2 S, anticorps ubiquitin conjugating enzyme E2 S S homeolog, anticorps ubiquitin conjugating enzyme E2 S L homeolog, anticorps UBE2S, anticorps Ube2s, anticorps ube2s, anticorps ATEG_00324, anticorps Smp_180170, anticorps MCYG_01532, anticorps ube2s.S, anticorps ube2s.L

Sujet:

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes \\\'Lys-11\\\'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating \\\'Lys-11\\\'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro, it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except \\\'Lys-48\\\'-linked polyubiquitination.

Aliases: AA409170 antibody, E2 EPF antibody, E2-EPF antibody, E2EPF antibody, EPF5 antibody, MGC101982 antibody, Ube2s antibody, UBE2S_HUMAN antibody, Ubiquitin carrier protein S antibody, Ubiquitin conjugating enzyme E2 24 kD antibody, Ubiquitin conjugating enzyme E2 24 kDa antibody, Ubiquitin conjugating enzyme E2 EPF5 antibody, Ubiquitin conjugating enzyme E2 S antibody, Ubiquitin conjugating enzyme E2S antibody, Ubiquitin protein ligase S antibody, Ubiquitin-conjugating enzyme E2 S antibody, Ubiquitin-conjugating enzyme E2-24 kDa antibody, Ubiquitin-conjugating enzyme E2-EPF5 antibody, Ubiquitin-protein ligase S antibody

UniProt: Q16763

Pathways: Ubiquitin Proteasome Pathway