UBE2W anticorps (AA 1-151) (Biotin)
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- Antigène Voir toutes UBE2W Anticorps
- UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))
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Épitope
- AA 1-151
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UBE2W est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Ubiquitin-conjugating enzyme E2 W protein (1-151AA)
- Isotype
- IgG
- Top Product
- Discover our top product UBE2W Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))
- Autre désignation
- UBE2W (UBE2W Produits)
- Synonymes
- anticorps UBE2W, anticorps im:6905459, anticorps si:ch211-193n21.4, anticorps ube2wa, anticorps UBC-16, anticorps UBC16, anticorps 6130401J04Rik, anticorps ubiquitin conjugating enzyme E2 W, anticorps ubiquitin-conjugating enzyme E2W (putative), anticorps ubiquitin conjugating enzyme E2 W (putative), anticorps ubiquitin conjugating enzyme E2W (putative), anticorps ubiquitin-conjugating enzyme E2W, anticorps UBE2W, anticorps ube2w, anticorps Ube2w
- Sujet
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Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3. After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. In vitro catalyzes \'Lys-11\'-linked polyubiquitination. Transfers ubiquitin in complex with RING/U-box type E3s that do not have active site cysteine residues to form thioester bonds with ubiquitin, and preferentially ubiquitinates the N-terminus of substrates, such as ATXN3, STUB1 and SUMO2.
Aliases: FLJ11011 antibody, hUBC 16 antibody, hUBC16 antibody, Probable ubiquitin conjugating enzyme E2 W antibody, Probable ubiquitin-conjugating enzyme E2 W antibody, UBC 16 antibody, UBC-16 antibody, UBC16 antibody, UBE 2W antibody, ube2w antibody, UBE2W_HUMAN antibody, Ubiquitin carrier protein W antibody, Ubiquitin conjugating enzyme 16 antibody, Ubiquitin conjugating enzyme E2 W antibody, Ubiquitin conjugating enzyme E2W antibody, Ubiquitin protein ligase W antibody, Ubiquitin-protein ligase W antibody
- UniProt
- Q96B02
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