UFM1 anticorps (AA 11-63) (Biotin)

N° du produit ABIN7174509

Détail du produit anti-UFM1 anticorps (Biotin)

Antigène: UFM1 (Ubiquitin-Fold Modifier 1 (UFM1))

Épitope: AA 11-63

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UFM1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ubiquitin-fold modifier 1 protein (11-63AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur UFM1

Antigène: UFM1 (Ubiquitin-Fold Modifier 1 (UFM1))

Autre désignation: UFM1 (UFM1 Produits)

Synonymes: anticorps T32E8.4, anticorps T32E8_4, anticorps BM-002, anticorps C13orf20, anticorps bA131P10.1, anticorps 1810045K17Rik, anticorps AI132708, anticorps AI463323, anticorps ENSMUSG00000074598, anticorps Gm10726, anticorps RGD1304890, anticorps UBFM1, anticorps ubfm1, anticorps wu:fa10f05, anticorps wu:fb72g01, anticorps zgc:55335, anticorps ubiquitin fold modifier 1, anticorps ubiquitin-fold modifier 1, anticorps ubiquitin-fold modifier, anticorps ubiquitin-fold modifier 1 L homeolog, anticorps UFM1, anticorps ufm1, anticorps CCP2, anticorps Ufm1, anticorps ufm1.L, anticorps PR46a

Sujet:

Background: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).

Aliases: BM 002 antibody, BM002 antibody, C13orf20 antibody, Chromosome 13 open reading frame 20 antibody, Ubiquitin fold modifier 1 antibody, Ubiquitin-fold modifier 1 antibody, UFM1 antibody, UFM1_HUMAN antibody

UniProt: P61960