SNF8 anticorps (AA 1-258) (Biotin)

N° du produit ABIN7175341

Détail du produit anti-SNF8 anticorps (Biotin)

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Épitope: AA 1-258

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNF8 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Vacuolar-sorting protein SNF8 protein (1-258AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SNF8

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Autre désignation: SNF8 (SNF8 Produits)

Synonymes: anticorps d11moh34, anticorps vps22, anticorps Dot3, anticorps EAP30, anticorps VPS22, anticorps D11moh34, anticorps RGD1310144, anticorps D11Moh34, anticorps D11MOH34, anticorps zgc:101578, anticorps SNF8, ESCRT-II complex subunit, anticorps eap30 subunit of ell complex, putative, anticorps EAP30 subunit of ELL complex, anticorps SNF8, ESCRT-II complex subunit S homeolog, anticorps SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae), anticorps snf8, anticorps TA17290, anticorps TVAG_107410, anticorps Bm1_05145, anticorps SNF8, anticorps Snf8, anticorps snf8.S

Sujet:

Background: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Aliases: Dot3 antibody, ELL associated protein of 30 kDa antibody, ELL-associated protein of 30 kDa antibody, ESCRT-II complex subunit VPS22 antibody, hVps22 antibody, snf8 antibody, SNF8 ESCRTII complex subunit homolog (S cerevisiae) antibody, SNF8_HUMAN antibody, Vacuolar sorting protein SNF8 antibody, Vacuolar-sorting protein SNF8 antibody, VPS22 antibody

UniProt: Q96H20