WDFY3 anticorps (AA 1-100)

N° du produit ABIN7175699

Détail du produit anti-WDFY3 anticorps

Antigène: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDFY3 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human WD repeat and FYVE domain-containing protein 3 protein (1-100AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur WDFY3

Antigène: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Autre désignation: WDFY3 (WDFY3 Produits)

Synonymes: anticorps ALFY, anticorps ZFYVE25, anticorps 2610509D04Rik, anticorps AW319683, anticorps B930017C24, anticorps BWF1, anticorps Bchs, anticorps D5Ertd66e, anticorps Ggtb3, anticorps mKIAA0993, anticorps WDFY family member 4, anticorps WD repeat and FYVE domain containing 3, anticorps WD repeat and FYVE domain-containing protein 3, anticorps WDFY4, anticorps WDFY3, anticorps MGYG_03998, anticorps Wdfy3

Sujet:

Background: Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.

Aliases: WDFY3 antibody, KIAA0993 antibody, WD repeat and FYVE domain-containing protein 3 antibody, Autophagy-linked FYVE protein antibody, Alfy antibody

UniProt: Q8IZQ1