WDR41 anticorps (AA 7-284)
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- Antigène Tous les produits WDR41
- WDR41 (WD Repeat Domain 41 (WDR41))
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Épitope
- AA 7-284
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WDR41 est non-conjugé
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Application
- ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human WD repeat-containing protein 41 protein (7-284AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- WDR41 (WD Repeat Domain 41 (WDR41))
- Autre désignation
- WDR41 (WDR41 Produits)
- Synonymes
- anticorps WDR41, anticorps MGC142930, anticorps wdr41, anticorps fj48d04, anticorps wu:fj48d04, anticorps zgc:110041, anticorps B830029I03Rik, anticorps MSTP048, anticorps WD repeat domain 41, anticorps Wdr41, anticorps WDR41, anticorps wdr41
- Sujet
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Background: Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190, PubMed:27103069, PubMed:27617292, PubMed:28195531). The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (PubMed:27103069). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069, PubMed:27617292).
Aliases: FLJ10904 antibody, MSTP048 antibody, WD repeat domain 41 antibody, WD repeat protein 41 antibody, WD repeat-containing protein 41 antibody, WDR 41 antibody, WDR41 antibody, WDR41_HUMAN antibody
- UniProt
- Q9HAD4
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