WDR41 anticorps (AA 7-284) (HRP)

N° du produit ABIN7175754

Détail du produit anti-WDR41 anticorps (HRP)

Antigène: WDR41 (WD Repeat Domain 41 (WDR41))

Épitope: AA 7-284

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR41 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human WD repeat-containing protein 41 protein (7-284AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur WDR41

Antigène: WDR41 (WD Repeat Domain 41 (WDR41))

Autre désignation: WDR41 (WDR41 Produits)

Synonymes: anticorps WDR41, anticorps MGC142930, anticorps wdr41, anticorps fj48d04, anticorps wu:fj48d04, anticorps zgc:110041, anticorps B830029I03Rik, anticorps MSTP048, anticorps WD repeat domain 41, anticorps Wdr41, anticorps WDR41, anticorps wdr41

Sujet:

Background: Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190, PubMed:27103069, PubMed:27617292, PubMed:28195531). The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (PubMed:27103069). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069, PubMed:27617292).

Aliases: FLJ10904 antibody, MSTP048 antibody, WD repeat domain 41 antibody, WD repeat protein 41 antibody, WD repeat-containing protein 41 antibody, WDR 41 antibody, WDR41 antibody, WDR41_HUMAN antibody

UniProt: Q9HAD4