WAC anticorps (AA 10-102)

N° du produit ABIN7175867

Détail du produit anti-WAC anticorps

Antigène: WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))

Épitope: AA 10-102

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WAC est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human WW domain-containing adapter protein with coiled-coil protein (10-102AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur WAC

Antigène: WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))

Autre désignation: WAC (WAC Produits)

Synonymes: anticorps BM-016, anticorps PRO1741, anticorps Wwp4, anticorps 1110067P07Rik, anticorps A230035H12Rik, anticorps AI256735, anticorps AI256776, anticorps DKFZp468H162, anticorps wac, anticorps wu:fc13f04, anticorps wu:fj68f01, anticorps zgc:55755, anticorps RGD1562407, anticorps zgc:101828, anticorps WW domain containing adaptor with coiled-coil, anticorps WW domain containing adaptor with coiled-coil a, anticorps WW domain containing adaptor with coiled-coil b, anticorps WAC, anticorps Wac, anticorps wac, anticorps waca, anticorps wacb

Sujet:

Background: Acts as a linker between gene transcription and histone H2B monoubiquitination at \\\'Lys-120\\\' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.

Aliases: 1110067P07Rik antibody, BA48B24 antibody, BA48B24.1 antibody, BM 016 antibody, FLJ31290 antibody, KIAA1844 antibody, MGC10753 antibody, OTTHUMP00000019380 antibody, OTTHUMP00000019382 antibody, PRO1741 antibody, wac antibody, WAC_HUMAN antibody, WW domain containing adapter protein with coiled coil antibody, WW domain containing adaptor with coiled coil antibody, WW domain-containing adapter protein with coiled-coil antibody, Wwp4 antibody

UniProt: Q9BTA9

Pathways: Chromatin Binding