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TRIM27 anticorps (AA 214-513)

TRIM27 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7176599
  • Antigène Voir toutes TRIM27 Anticorps
    TRIM27 (Tripartite Motif Containing 27 (TRIM27))
    Épitope
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 214-513
    Reactivité
    • 40
    • 21
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 38
    • 2
    Lapin
    Clonalité
    • 38
    • 2
    Polyclonal
    Conjugué
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TRIM27 est non-conjugé
    Application
    • 24
    • 14
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Zinc finger protein RFP protein (214-513AA)
    Isotype
    IgG
    Top Product
    Discover our top product TRIM27 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    TRIM27 (Tripartite Motif Containing 27 (TRIM27))
    Autre désignation
    TRIM27 (TRIM27 Produits)
    Synonymes
    anticorps RFP, anticorps RNF76, anticorps AW538890, anticorps Gm19403, anticorps Rfp, anticorps TRIM27, anticorps Rfp1, anticorps tripartite motif containing 27, anticorps tripartite motif-containing 27, anticorps TRIM27, anticorps Trim27
    Sujet

    Background: E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity, mediates the formation of \\\'Lys-48\\\'-linked polyubiquitin chains, the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of \\\'Lys-63\\\'-linked polyubiquitin chains at \\\'Lys-220\\\' of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.

    Aliases: AW538890 antibody, DAAP-182E11.3 antibody, MGC189472 antibody, OTTHUMP00000029314 antibody, Ret finger protein antibody, RFP antibody, RFP transforming protein antibody, Rfp1 antibody, RING finger protein 76 antibody, RNF76 antibody, TRI27_HUMAN antibody, TRIM 27 antibody, Trim27 antibody, Tripartite motif containing 27 antibody, Tripartite motif containing protein 27 antibody, Tripartite motif protein TRIM27 antibody, Tripartite motif-containing protein 27 antibody, Zinc finger protein RFP antibody

    UniProt
    P14373
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