TRIM27 anticorps (AA 214-513)
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- Antigène Voir toutes TRIM27 Anticorps
- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
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Épitope
- AA 214-513
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TRIM27 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Zinc finger protein RFP protein (214-513AA)
- Isotype
- IgG
- Top Product
- Discover our top product TRIM27 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
- Autre désignation
- TRIM27 (TRIM27 Produits)
- Synonymes
- anticorps RFP, anticorps RNF76, anticorps AW538890, anticorps Gm19403, anticorps Rfp, anticorps TRIM27, anticorps Rfp1, anticorps tripartite motif containing 27, anticorps tripartite motif-containing 27, anticorps TRIM27, anticorps Trim27
- Sujet
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Background: E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity, mediates the formation of \\\'Lys-48\\\'-linked polyubiquitin chains, the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of \\\'Lys-63\\\'-linked polyubiquitin chains at \\\'Lys-220\\\' of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.
Aliases: AW538890 antibody, DAAP-182E11.3 antibody, MGC189472 antibody, OTTHUMP00000029314 antibody, Ret finger protein antibody, RFP antibody, RFP transforming protein antibody, Rfp1 antibody, RING finger protein 76 antibody, RNF76 antibody, TRI27_HUMAN antibody, TRIM 27 antibody, Trim27 antibody, Tripartite motif containing 27 antibody, Tripartite motif containing protein 27 antibody, Tripartite motif protein TRIM27 antibody, Tripartite motif-containing protein 27 antibody, Zinc finger protein RFP antibody
- UniProt
- P14373
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