METRNL anticorps (AA 46-311)

N° du produit ABIN7177681

Détail du produit anti-METRNL anticorps

Antigène: METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))

Épitope: AA 46-311

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METRNL est non-conjugé

Application: ELISA, Western Blotting (WB)

Réactivité croisée: Souris, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Mouse Meteorin-like protein (46-311AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur METRNL

Antigène: METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))

Autre désignation: Metrnl (METRNL Produits)

Synonymes: anticorps 9430048M07Rik, anticorps BC019776, anticorps fc90a08, anticorps fj23b04, anticorps wu:fc90a08, anticorps wu:fj23b04, anticorps zgc:56225, anticorps meteorin like, glial cell differentiation regulator, anticorps meteorin, glial cell differentiation regulator-like, anticorps meteorin-like, glial cell differentiation regulator, anticorps meteorin, glial cell differentiation regulator-like L homeolog, anticorps METRNL, anticorps Metrnl, anticorps metrnl.L, anticorps metrnl

Sujet:

Background: Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.

Aliases: MetrnlMeteorin-like protein antibody, Subfatin antibody

UniProt: Q8VE43