TXNIP anticorps (AA 1-397)
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- Antigène Voir toutes TXNIP Anticorps
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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Épitope
- AA 1-397
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TXNIP est non-conjugé
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Application
- ELISA
- Réactivité croisée
- Souris
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Mouse Thioredoxin-interacting protein (1-397AA)
- Isotype
- IgG
- Top Product
- Discover our top product TXNIP Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
- Autre désignation
- Txnip (TXNIP Produits)
- Synonymes
- anticorps EST01027, anticorps HHCPA78, anticorps THIF, anticorps VDUP1, anticorps Gm348, anticorps Trf3, anticorps TBP2, anticorps TRF3, anticorps 1200008J08Rik, anticorps AA682105, anticorps Hyplip1, anticorps Tbp-2, anticorps Vdup1, anticorps sb:cb368, anticorps txnip, anticorps thioredoxin interacting protein, anticorps TATA box binding protein like 2, anticorps TATA-box binding protein like 2, anticorps thioredoxin interacting protein L homeolog, anticorps thioredoxin interacting protein a, anticorps TXNIP, anticorps Tbpl2, anticorps TBPL2, anticorps Txnip, anticorps txnip.L, anticorps txnip, anticorps txnipa
- Sujet
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Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.
Aliases: Txnip antibody, Vdup1 antibody, Thioredoxin-interacting protein antibody, Vitamin D3 up-regulated protein 1 antibody
- UniProt
- Q8BG60
- Pathways
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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