Ephrin A5 anticorps (AA 21-203) (FITC)

N° du produit ABIN7178847

Détail du produit anti-Ephrin A5 anticorps (FITC)

Antigène: Ephrin A5 (EFNA5)

Épitope: AA 21-203

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ephrin A5 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Réactivité croisée: Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Rat Ephrin-A5 protein (21-203AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Ephrin A5

Antigène: Ephrin A5 (EFNA5)

Autre désignation: Efna5 (EFNA5 Produits)

Synonymes: anticorps EFNA5, anticorps af1, anticorps efl5, anticorps rags, anticorps eplg7, anticorps lerk7, anticorps AL-1, anticorps AV158822, anticorps EFL-5, anticorps Ephrin-A5, anticorps Epl7, anticorps LERK-7, anticorps RAGS, anticorps Lerk7, anticorps AF1, anticorps EFL5, anticorps EPLG7, anticorps GLC1M, anticorps LERK7, anticorps ephrin A5, anticorps EFNA5, anticorps efna5, anticorps Efna5

Sujet:

Background: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion

Aliases: Efna5 antibody, Eplg7 antibody, Lerk7 antibody, Ephrin-A5 antibody, AL-1 antibody, EPH-related receptor tyrosine kinase ligand 7 antibody, LERK-7 antibody

UniProt: P97605

Pathways: Signalisation RTK