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Sortilin 1 anticorps (AA 610-754)

SORT1 Reactivité: Rat ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7179077
  • Antigène Voir toutes Sortilin 1 (SORT1) Anticorps
    Sortilin 1 (SORT1)
    Épitope
    • 16
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 610-754
    Reactivité
    • 45
    • 37
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 46
    • 6
    • 2
    Lapin
    Clonalité
    • 49
    • 5
    Polyclonal
    Conjugué
    • 24
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Sortilin 1 est non-conjugé
    Application
    • 38
    • 17
    • 17
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Rat
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Rat Sortilin protein (610-754AA)
    Isotype
    IgG
    Top Product
    Discover our top product SORT1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Sortilin 1 (SORT1)
    Autre désignation
    Sort1 (SORT1 Produits)
    Synonymes
    anticorps SORT1, anticorps 19.m02079, anticorps gp95, anticorps ldlcq6, anticorps sortilin, anticorps Gp95, anticorps LDLCQ6, anticorps NT3, anticorps 2900053A11Rik, anticorps AI852375, anticorps Ntr3, anticorps Ntsr3, anticorps Nt3, anticorps Nts3, anticorps sort1, anticorps zgc:85953, anticorps sortilin 1, anticorps sortilin, anticorps sortilin 1 S homeolog, anticorps sortilin 1a, anticorps SORT1, anticorps TP01_0016, anticorps BBOV_I002730, anticorps sort1.S, anticorps Sort1, anticorps sort1a
    Sujet

    Background: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

    Aliases: Sort1 antibody, Sortilin antibody, Glycoprotein 110 antibody, Gp110 antibody, Neurotensin receptor 3 antibody, NTR3 antibody

    UniProt
    O54861
    Pathways
    Neurotrophin Signaling Pathway
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