Streptococcal Pyrogenic Exotoxin B (SPEB) (AA 146-398) anticorps

N° du produit ABIN7179505

Détail du produit

Antigène: Streptococcal Pyrogenic Exotoxin B (SPEB)

Épitope: AA 146-398

Reactivité: Streptococcus pyogenes

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Réactivité croisée: Streptococcus pyogenes

Purification: >95%, Protein G purified

Immunogène: Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Streptococcal Pyrogenic Exotoxin B (SPEB)

Autre désignation: speB (SPEB Produits)

Synonymes: anticorps streptococcal pyrogenic exotoxin B, anticorps speB

Sujet:

Background: Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).

Aliases: speB antibody, M28_Spy1721 antibody, Streptopain antibody, EC 3.4.22.10 antibody, Exotoxin type B antibody, SPE B antibody, Streptococcal cysteine proteinase antibody, Streptococcus peptidase A antibody, SPP antibody

UniProt: Q48R29