CTNND1 anticorps (Tyr228)

N° du produit ABIN7179986

Détail du produit anti-CTNND1 anticorps

Antigène: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Épitope: Tyr228

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTNND1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from Human Catenin-delta1 around the phosphorylation site of tyrosine 228 (D-N-Y(p)-G-S).

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CTNND1

Antigène: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Autre désignation: CTNND1 (CTNND1 Produits)

Synonymes: anticorps CAS, anticorps CTNND, anticorps P120CAS, anticorps P120CTN, anticorps p120, anticorps p120(CAS), anticorps p120(CTN), anticorps Catns, anticorps cas, anticorps Xp120, anticorps ctnnd, anticorps p120cas, anticorps p120ctn, anticorps p120(ctn), anticorps Xp120(ctn), anticorps p120-catenin, anticorps CTNND1, anticorps AA409437, anticorps AU019353, anticorps Ctnnd, anticorps P120, anticorps mKIAA0384, anticorps catenin delta 1, anticorps catenin (cadherin-associated protein), delta 1, anticorps catenin (cadherin associated protein), delta 1, anticorps catenin delta 1 L homeolog, anticorps CTNND1, anticorps Ctnnd1, anticorps ctnnd1, anticorps ctnnd1.L

Sujet:

Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway By similarity. Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.Keirsebilck A., Genomics 50:129-146(1998).Nagase T., DNA Res. 4:141-150(1997).W.S., Sherwood J.K., Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.

Aliases: Cadherin associated Src substrate antibody, Cadherin-associated Src substrate antibody, CAS antibody, Catenin (cadherin associated protein) delta 1 antibody, Catenin delta 1 antibody, Catenin delta antibody, Catenin delta-1 antibody, CTND1_HUMAN antibody, CTNND 1 antibody, CTNND antibody, CTNND1 antibody, delta 1 Catenin antibody, KIAA0384 antibody, p120 antibody, P120 CAS antibody, p120 catenin antibody, P120 CTN antibody, p120(cas) antibody, p120(ctn) antibody, P120CAS antibody, P120CTN antibody

UniProt: O60716

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling