CNOT2 anticorps (Ser101)

N° du produit ABIN7179994

Détail du produit anti-CNOT2 anticorps

Antigène: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Épitope: Ser101

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from Human CNOT2 around the phosphorylation site of serine 101 (S-L-S(p)-Q-G).

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CNOT2

Antigène: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Autre désignation: CNOT2 (CNOT2 Produits)

Synonymes: anticorps CDC36, anticorps NOT2, anticorps NOT2H, anticorps 2600016M12Rik, anticorps 2810470K03Rik, anticorps AA537049, anticorps AA959607, anticorps AW557563, anticorps C79650, anticorps cdc36, anticorps not2, anticorps cnot2, anticorps CCR4-NOT transcription complex subunit 2, anticorps CCR4-NOT transcription complex, subunit 2, anticorps CCR4-NOT transcription complex subunit 2 S homeolog, anticorps CNOT2, anticorps Cnot2, anticorps cnot2.S, anticorps cnot2

Sujet:

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.

Albert T.K., Nucleic Acids Res. 28:809-817(2000).
Zhang Q.-H., Genome Res. 10:1546-1560(2000).
Ota T., Nat. Genet. 36:40-45(2004).

Aliases: CCR4 associated factor 2 antibody, CCR4 NOT transcription complex subunit 2 antibody, CCR4-associated factor 2 antibody, CCR4-NOT transcription complex subunit 2 antibody, CDC36 antibody, CNOT2 antibody, CNOT2_HUMAN antibody, HSPC131 antibody, MSTP046 antibody, Negative regulator of transcription 2 antibody, NOT2 (negative regulator of transcription 2 yeast) homolog antibody, NOT2 antibody, NOT2H antibody

UniProt: Q9NZN8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance