FRS2 anticorps (Tyr196)

N° du produit ABIN7180012

Détail du produit anti-FRS2 anticorps

Antigène: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Épitope: Tyr196

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FRS2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from Human FRS2 around the phosphorylation site of tyrosine 196 (H-T-Y(p)-V-N).

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FRS2

Antigène: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Autre désignation: FRS2 (FRS2 Produits)

Synonymes: anticorps frs2, anticorps wu:fd21h10, anticorps zgc:91973, anticorps FRS2A, anticorps FRS2alpha, anticorps SNT, anticorps SNT-1, anticorps SNT1, anticorps 4732458E18, anticorps C330018A15Rik, anticorps Frs2alpha, anticorps fibroblast growth factor receptor substrate 2, anticorps fibroblast growth factor receptor substrate 2b, anticorps FRS2, anticorps frs2b, anticorps Frs2

Sujet:

Background: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

The MGC Project Team, Genome Res. 14:2121-2127(2004).
Xu H., J. Biol. Chem. 273:17987-17990(1998).
Meakin S.O., J. Biol. Chem. 274:9861-9870(1999).

Aliases: FGFR signaling adaptor SNT antibody, FGFR signalling adaptor antibody, FGFR substrate 2 antibody, FGFR-signaling adaptor SNT antibody, Fibroblast growth factor receptor substrate 2 antibody, FRS 2 antibody, FRS2 antibody, FRS2_HUMAN antibody, FRS2A antibody, FRS2alpha antibody, SNT 1 antibody, SNT antibody, SNT-1 antibody, SNT1 antibody, Suc 1 Associated Neurotrophic Factor Target antibody, Suc1 associated neurotrophic factor target 1 antibody, Suc1-associated neurotrophic factor target 1 antibody

UniProt: Q8WU20

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2