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ILK anticorps (Ser246)

ILK Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7180030
  • Antigène Voir toutes ILK Anticorps
    ILK (Integrin-Linked Kinase (ILK))
    Épitope
    • 26
    • 24
    • 16
    • 15
    • 10
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser246
    Reactivité
    • 147
    • 60
    • 53
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 155
    • 6
    • 1
    Lapin
    Clonalité
    • 155
    • 7
    Polyclonal
    Conjugué
    • 61
    • 14
    • 14
    • 12
    • 8
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp ILK est non-conjugé
    Application
    • 109
    • 86
    • 53
    • 40
    • 39
    • 20
    • 17
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain, Souris
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    Synthesized non-phosphopeptide derived from Human ILK around the phosphorylation site of serine 246 (I-F-S(p)-H-P).
    Isotype
    IgG
    Top Product
    Discover our top product ILK Anticorps primaire
  • Indications d'application
    WB:1:500-1:3000, IHC:1:50-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ILK (Integrin-Linked Kinase (ILK))
    Autre désignation
    ILK (ILK Produits)
    Synonymes
    anticorps CG10504, anticorps CT29478, anticorps DmILK, anticorps Dmel\\CG10504, anticorps ILK, anticorps ilk, anticorps l(3)78Ca, anticorps p59, anticorps AA511515, anticorps ESTM24, anticorps zgc:65842, anticorps ILK-1, anticorps ILK-2, anticorps P59, anticorps p59ILK, anticorps Integrin linked kinase, anticorps integrin linked kinase, anticorps integrin linked kinase S homeolog, anticorps integrin-linked protein kinase, anticorps integrin-linked kinase, anticorps Ilk, anticorps ILK, anticorps ilk.S, anticorps CpipJ_CPIJ016644, anticorps Bm1_20815, anticorps Tsp_07213, anticorps Tsp_07224, anticorps Tsp_15354, anticorps ilk
    Sujet

    Background: Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

    Hannigan G.E.,Nature 379:91-96(1996).
    Janji B.,Oncogene 19:3069-3077(2000).
    Tadic B.,Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.

    Aliases: 59 kDa serine/threonine protein kinase antibody, 59 kDa serine/threonine-protein kinase antibody, DKFZp686F1765 antibody, Epididymis secretory protein Li 28 antibody, HEL S 28 antibody, ILK 1 antibody, ILK 2 antibody, ILK antibody, ILK-1 antibody, ILK-2 antibody, ILK_HUMAN antibody, ILK1 antibody, ILK2 antibody, Integrin linked kinase 2 antibody, Integrin linked Kinase antibody, Integrin linked protein kinase antibody, Integrin-linked protein kinase antibody, p59 antibody, p59ILK antibody

    UniProt
    Q13418
    Pathways
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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