ILK anticorps (Ser246)
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- Antigène Voir toutes ILK Anticorps
- ILK (Integrin-Linked Kinase (ILK))
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Épitope
- Ser246
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ILK est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain, Souris
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized non-phosphopeptide derived from Human ILK around the phosphorylation site of serine 246 (I-F-S(p)-H-P).
- Isotype
- IgG
- Top Product
- Discover our top product ILK Anticorps primaire
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- Indications d'application
- WB:1:500-1:3000, IHC:1:50-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ILK (Integrin-Linked Kinase (ILK))
- Autre désignation
- ILK (ILK Produits)
- Synonymes
- anticorps CG10504, anticorps CT29478, anticorps DmILK, anticorps Dmel\\CG10504, anticorps ILK, anticorps ilk, anticorps l(3)78Ca, anticorps p59, anticorps AA511515, anticorps ESTM24, anticorps zgc:65842, anticorps ILK-1, anticorps ILK-2, anticorps P59, anticorps p59ILK, anticorps Integrin linked kinase, anticorps integrin linked kinase, anticorps integrin linked kinase S homeolog, anticorps integrin-linked protein kinase, anticorps integrin-linked kinase, anticorps Ilk, anticorps ILK, anticorps ilk.S, anticorps CpipJ_CPIJ016644, anticorps Bm1_20815, anticorps Tsp_07213, anticorps Tsp_07224, anticorps Tsp_15354, anticorps ilk
- Sujet
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Background: Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Hannigan G.E.,Nature 379:91-96(1996).
Janji B.,Oncogene 19:3069-3077(2000).
Tadic B.,Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.Aliases: 59 kDa serine/threonine protein kinase antibody, 59 kDa serine/threonine-protein kinase antibody, DKFZp686F1765 antibody, Epididymis secretory protein Li 28 antibody, HEL S 28 antibody, ILK 1 antibody, ILK 2 antibody, ILK antibody, ILK-1 antibody, ILK-2 antibody, ILK_HUMAN antibody, ILK1 antibody, ILK2 antibody, Integrin linked kinase 2 antibody, Integrin linked Kinase antibody, Integrin linked protein kinase antibody, Integrin-linked protein kinase antibody, p59 antibody, p59ILK antibody
- UniProt
- Q13418
- Pathways
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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