MITF anticorps (Ser73, Ser180)

N° du produit ABIN7180048

Détail du produit anti-MITF anticorps

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Épitope: Ser73, Ser180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MITF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from Human MITF around the phosphorylation site of serine 180/73 (P-N-S(p)-P-M).

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MITF

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: MITF (MITF Produits)

Synonymes: anticorps MITF, anticorps ws2a, anticorps mitfa, anticorps MITF-A, anticorps LOC100313655, anticorps mitfb, anticorps CMM8, anticorps MI, anticorps WS2, anticorps WS2A, anticorps bHLHe32, anticorps BCC2, anticorps Bhlhe32, anticorps Gsfbcc2, anticorps Vitiligo, anticorps Wh, anticorps bw, anticorps mi, anticorps vit, anticorps MITF-H, anticorps MITF-M, anticorps CMI9, anticorps melanogenesis associated transcription factor, anticorps microphthalmia-associated transcription factor, anticorps microphthalmia-associated transcription factor S homeolog, anticorps Microphthalmia, anticorps MITF, anticorps mitf, anticorps LOC100313655, anticorps mitf.S, anticorps LOC100534525, anticorps MICROP, anticorps Mitf

Sujet:

Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

J

Aliases: BHLHE32 antibody, bHLHe32 antibody, Class E basic helix-loop-helix protein 32 antibody, CMM8 antibody, Homolog of mouse microphthalmia antibody, Mi antibody, Microphthalmia associated transcription factor antibody, Microphthalmia, mouse, homolog of antibody, Microphthalmia-associated transcription factor antibody, MITF antibody, MITF_HUMAN antibody, mitfa antibody, nacre antibody, WS2 antibody, WS2A antibody, z3A.1 antibody

UniProt: O75030

Pathways: Chromatin Binding