Vitamin D Receptor anticorps (Ser51)

N° du produit ABIN7180105

Détail du produit anti-Vitamin D Receptor anticorps

Antigène: Vitamin D Receptor (VDR)

Épitope: Ser51

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vitamin D Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from Human Vitamin D3 Receptor around the phosphorylation site of serine 51 (R-R-S(p)-M-K).

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Vitamin D Receptor

Antigène: Vitamin D Receptor (VDR)

Autre désignation: VDR (VDR Produits)

Synonymes: anticorps vdrbeta, anticorps vdr0, anticorps LOC100136219, anticorps NR1I1-B, anticorps gb:dq017633, anticorps vdr-b, anticorps Ci-VDR-b, anticorps VDR, anticorps LOC100221284, anticorps vdr-A, anticorps xVDR, anticorps Nr1i1, anticorps vdr, anticorps NR1I1, anticorps PPP1R163, anticorps vitamin D (1,25- dihydroxyvitamin D3) receptor, anticorps vitamin D receptor, anticorps vitamin D3 receptor A, anticorps vitamin D receptor b, anticorps nuclear receptor VDR-b, anticorps vitamin D (1,25- dihydroxyvitamin D3) receptor L homeolog, anticorps vitamin D (1,25-dihydroxyvitamin D3) receptor, anticorps vitamin D receptor a, anticorps vdr, anticorps vdr0, anticorps VDR, anticorps LOC100136219, anticorps vdrb, anticorps vdr-b, anticorps vdr.L, anticorps Vdr, anticorps vdra

Classe de substances: Chemical

Sujet:

Background: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

Baker A.R., Proc. Natl. Acad. Sci. U.S.A. 85:3294-3298(1988).
Goto H., Biochim. Biophys. Acta 1132:103-108(1992).
Miyamoto K., Mol. Endocrinol. 11:1165-1179(1997).

Aliases: 1 25 dihydroxyvitamin D3 receptor antibody, 1 antibody, 1,25 dihydroxyvitamin D3 receptor antibody, 1,25-@dihydroxyvitamin D3 receptor antibody, 25-dihydroxyvitamin D3 receptor antibody, Member 1 antibody, NR1I1 antibody, Nuclear receptor subfamily 1 group I member 1 antibody, PPP1R163 antibody, Protein phosphatase 1, regulatory subunit 163 antibody, VDR antibody, VDR_HUMAN antibody, Vitamin D (1,25- dihydroxyvitamin D3) receptor antibody, Vitamin D hormone receptor antibody, Vitamin D nuclear receptor variant 1 antibody, Vitamin D receptor antibody, Vitamin D3 receptor antibody

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway