CHRNA1 anticorps (C-Term)

N° du produit ABIN7180140

Détail du produit anti-CHRNA1 anticorps

Antigène: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human CHRNA10.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CHRNA1

Antigène: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Autre désignation: CHRNA1 (CHRNA1 Produits)

Synonymes: anticorps CHRNA1, anticorps ACHRA, anticorps ACHRD, anticorps CHRNA, anticorps CMS2A, anticorps FCCMS, anticorps SCCMS, anticorps NACHRA1, anticorps AI385656, anticorps AI608266, anticorps Achr-1, anticorps Acra, anticorps cholinergic receptor nicotinic alpha 1 subunit, anticorps cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), anticorps CHRNA1, anticorps Chrna1

Sujet:

Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Sgard F., Mol. Pharmacol. 61:150-159(2002).
Lustig L.R., Genomics 73:272-283(2001).
Vandenberk I., Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.

Aliases: Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody, ACH10_HUMAN antibody, Alpha 10 nAChR antibody, Cholinergic receptor nicotinic alpha 10 antibody, Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody, Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody, CHRNA 10 antibody, CHRNA10 antibody, NACHR alpha 10 antibody, NACHR alpha-10 antibody, NACHRA10 antibody, Neuronal acetylcholine receptor protein subunit alpha 10 antibody, Neuronal acetylcholine receptor subunit alpha-10 antibody, Nicotinic acetylcholine receptor subunit alpha 10 antibody, Nicotinic acetylcholine receptor subunit alpha-10 antibody, OTTHUMP00000013620 antibody

UniProt: Q9GZZ6

Pathways: Skeletal Muscle Fiber Development