DMGDH anticorps (C-Term)

N° du produit ABIN7180160

Détail du produit anti-DMGDH anticorps

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMGDH est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human DMGDH.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DMGDH

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Autre désignation: DMGDH (DMGDH Produits)

Synonymes: anticorps MGC132281, anticorps DMGDHD, anticorps ME2GLYDH, anticorps Me2GlyDH, anticorps 1200014D15Rik, anticorps AI787269, anticorps dimethylglycine dehydrogenase, anticorps dimethylglycine dehydrogenase L homeolog, anticorps D-amino-acid oxidase, anticorps Dimethylglycine dehydrogenase, anticorps glycine cleavage system protein T, anticorps dimethylglycine dehydrogenase precursor, anticorps DMGDH, anticorps dmgdh.L, anticorps dmgdh, anticorps SAR11_1253, anticorps EAMY_RS27375, anticorps EAMY_RS33570, anticorps VDBG_06516, anticorps Sinme_2570, anticorps HALXA_RS03495, anticorps Dmgdh

Sujet:

Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Binzak B.A., Mol. Genet. Metab. 69:181-187(2000).
Binzak B.A., Am. J. Hum. Genet. 68:839-847(2001).
Moolenaar S.H., Clin. Chem. 45:459-464(1999)

Aliases: Dimethylglycine dehydrogenase antibody, Dimethylglycine dehydrogenase, mitochondrial antibody, Dmgdh antibody, M2GD_HUMAN antibody, ME2GLYDH antibody, mitochondrial antibody

UniProt: Q9UI17