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Dynamin 1-Like anticorps (C-Term)

DNM1L Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7180161
  • Antigène Voir toutes Dynamin 1-Like (DNM1L) Anticorps
    Dynamin 1-Like (DNM1L)
    Épitope
    • 23
    • 11
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 58
    • 52
    • 35
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 65
    • 8
    Lapin
    Clonalité
    • 65
    • 8
    Polyclonal
    Conjugué
    • 32
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Dynamin 1-Like est non-conjugé
    Application
    • 33
    • 27
    • 18
    • 13
    • 13
    • 12
    • 9
    • 9
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    Synthesized peptide derived from C-terminal of Human DNM1L.
    Isotype
    IgG
    Top Product
    Discover our top product DNM1L Anticorps primaire
  • Indications d'application
    WB:1:500-1:3000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Dynamin 1-Like (DNM1L)
    Autre désignation
    DNM1L (DNM1L Produits)
    Synonymes
    anticorps DLP1, anticorps DRP1, anticorps DVLP, anticorps DYMPLE, anticorps EMPF, anticorps HDYNIV, anticorps 6330417M19Rik, anticorps AI450666, anticorps Dlp1, anticorps Dnmlp1, anticorps Drp1, anticorps python, anticorps Dnml1, anticorps dnm1l, anticorps MGC53850, anticorps zgc:66163, anticorps DNM1L, anticorps 18.m06247, anticorps CG3210, anticorps DRP, anticorps Dmel\CG3210, anticorps Dnm1/Drp1, anticorps Drp, anticorps Drp-1, anticorps drp-1, anticorps drp1, anticorps frat, anticorps l(2)22Fc, anticorps l(2)22Fd, anticorps l(2)ND2, anticorps l(2)ND3, anticorps dynamin 1 like, anticorps dynamin 1-like, anticorps dynamin 1-like L homeolog, anticorps dynamin-1-like, anticorps dynamin-1-like protein, anticorps dynamin-like protein, anticorps Dynamin related protein 1, anticorps DNM1L, anticorps Dnm1l, anticorps dnm1l.L, anticorps dnm1l, anticorps LOC100369408, anticorps LOC411472, anticorps dyn1, anticorps cgd1_580, anticorps EHI_052740, anticorps PVX_092875, anticorps BBOV_II002980, anticorps Drp1
    Sujet

    Background: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L)which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.

    Shin H.-W., J. Biochem. 122:525-530(1997).
    Hong Y.-R., Biochem. Biophys. Res. Commun. 249:697-703(1998).
    Imoto M., J. Cell Sci. 111:1341-1349(1998).

    Aliases: DLP1 antibody, dnm1l antibody, DNM1L_HUMAN antibody, Dnm1p/Vps1p-like protein antibody, dnml1 antibody, DRP1 antibody, DVLP antibody, Dymple antibody, Dynamin 1 like antibody, Dynamin family member proline-rich carboxyl-terminal domain less antibody, Dynamin like protein antibody, Dynamin related protein 1 antibody, Dynamin-1-like protein antibody, Dynamin-like protein 4 antibody, Dynamin-like protein antibody, Dynamin-like protein IV antibody, Dynamin-related protein 1 antibody, DYNIV 11 antibody, EMPF antibody, EMPF1 antibody, FLJ41912 antibody, HdynIV antibody, VPS1 antibody

    UniProt
    O00429
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