GNE anticorps (C-Term)

N° du produit ABIN7180179

Détail du produit anti-GNE anticorps

Antigène: GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human GNE.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GNE

Antigène: GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))

Autre désignation: GNE (GNE Produits)

Synonymes: anticorps DMRV, anticorps GLCNE, anticorps IBM2, anticorps UAE1, anticorps zgc:77657, anticorps GNE, anticorps MGC145505, anticorps NM, anticorps Uae1, anticorps 2310066H07Rik, anticorps glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase, anticorps GNE, anticorps gne, anticorps Gne

Sujet:

Background: Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.

Lucka L., FEBS Lett. 454:341-344(1999).
Seppala R., Am. J. Hum. Genet. 64:1563-1569(1999).
Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.

Aliases: 2310066H07Rik antibody, Bifunctional UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase antibody, DMRV antibody, GLCNE_HUMAN antibody, Glucosamine (UDP N acetyl) 2 epimerase/N acetylmannosamine kinase antibody, GNE antibody, IBM2 antibody, ManAc kinase antibody, N acylmannosamine kinase antibody, N-acetylmannosamine kinase antibody, NM antibody, RP23-209M8.6 antibody, Uae1 antibody, UDP GlcNAc 2 epimerase antibody, UDP GlcNAc 2 epimerase/ManAc kinase antibody, UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase antibody, UDP-GlcNAc-2-epimerase antibody, UDP-GlcNAc-2-epimerase/ManAc kinase antibody, Uridine diphosphate N acetylglucosamine 2 epimerase antibody, Uridine diphosphate-N-acetylglucosamine-2-epimerase antibody

UniProt: Q9Y223