Pre-mRNA Branch Site Protein p14 (SF3B14) (C-Term) anticorps

N° du produit ABIN7180242

Détail du produit

Antigène: Pre-mRNA Branch Site Protein p14 (SF3B14)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human SF3B14.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Pre-mRNA Branch Site Protein p14 (SF3B14)

Autre désignation: SF3B6 (SF3B14 Produits)

Synonymes: anticorps 6030419K15Rik, anticorps AV001342, anticorps Sf3b14, anticorps zgc:86708, anticorps HSPC175, anticorps Ht006, anticorps P14, anticorps SAP14, anticorps SF3B14a, anticorps splicing factor 3B, subunit 6, anticorps splicing factor 3b, subunit 6, anticorps splicing factor 3b subunit 6 S homeolog, anticorps splicing factor 3b subunit 6, anticorps Sf3b6, anticorps sf3b6, anticorps sf3b6.S, anticorps SF3B6

Sujet:

Background: Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.

Will C.L., EMBO J. 20:4536-4546(2001).
Lai C.-H., Genome Res. 10:703-713(2000).
Zhang Q.-H., Genome Res. 10:1546-1560(2000).

Aliases: Ht006 antibody, P14 antibody, PM14_HUMAN antibody, Pre mRNA branch site protein p14 antibody, Pre-mRNA branch site protein p14 antibody, SAP14 antibody, SF3B 14 kDa subunit antibody, SF3B14 antibody, SF3B14a antibody, Splicing factor 3B, 14 kDa subunit antibody

UniProt: Q9Y3B4