SHB anticorps (C-Term)

N° du produit ABIN7180246

Détail du produit anti-SHB anticorps

Antigène: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHB est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human SHB.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SHB

Antigène: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Autre désignation: SHB (SHB Produits)

Synonymes: anticorps SHB, anticorps RP11-3J10.8, anticorps bA3J10.2, anticorps RGD1565350, anticorps BC028832, anticorps SH2 domain containing adaptor protein B, anticorps src homology 2 domain-containing transforming protein B, anticorps SHB, anticorps Shb

Sujet:

Background: Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Welsh M., Oncogene 9:19-27(1994).
Humphray S.J., Nature 429:369-374(2004).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

Aliases: bA3J10.2 antibody, OTTHUMP00000021397 antibody, RP11 3J10.8 antibody, RP113J10.8 antibody, SH2 domain containing adapter protein B antibody, SH2 domain-containing adapter protein B antibody, SHB (Src homology 2 domain containing) adaptor protein B antibody, SHB adaptor protein (a Src homology 2 protein) antibody, SHB adaptor protein antibody, Shb antibody, SHB_HUMAN antibody, Src homology 2 domain containing adaptor protein B antibody, Src homology 2 protein antibody

UniProt: Q15464