GRM8 anticorps

N° du produit ABIN7181343

Détail du produit anti-GRM8 anticorps

Antigène: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from Human GluR8.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GRM8

Antigène: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Autre désignation: GRM8 (GRM8 Produits)

Synonymes: anticorps mGluR8, anticorps GRM8, anticorps MGLUR8, anticorps GLUR8, anticorps GPRC1H, anticorps mGlu8, anticorps A230002O04, anticorps Gprc1h, anticorps Glur8, anticorps Mglur8, anticorps mGluR8b, anticorps mGlur, anticorps glutamate metabotropic receptor 8, anticorps metabotropic glutamate receptor 8, anticorps glutamate receptor, metabotropic 8, anticorps GRM8, anticorps MGLUR8, anticorps LOAG_14062, anticorps Grm8

Sujet:

Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Patrick. M. Downey, J Biomol Screen, Dec 2005, 10: 841 - 848.
RJ Wenthold, J. Biol. Chem., Jan 1994, 269: 1332 - 1339.
Toshiaki Watanabe, Cancer Res., Oct 2006, 66: 9804 - 9808.
V. Bruno, J. Neurosci., Sep 2000, 20: 6413.

Aliases: FLJ41058 antibody, GLUR8 antibody, Glutamate receptor metabotropic 8 antibody, GPRC1H antibody, GRM8 antibody, GRM8_HUMAN antibody, Metabotropic glutamate receptor 8 antibody, MGC126724 antibody, mGlu8 antibody, mGluR8 antibody

UniProt: O00222

Pathways: cAMP Metabolic Process, Synaptic Membrane