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Neuregulin 1 anticorps (Isoform 10)

NRG1 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7182178
  • Antigène Voir toutes Neuregulin 1 (NRG1) Anticorps
    Neuregulin 1 (NRG1)
    Épitope
    • 16
    • 16
    • 15
    • 10
    • 9
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform 10
    Reactivité
    • 100
    • 78
    • 54
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 118
    • 9
    Lapin
    Clonalité
    • 118
    • 9
    Polyclonal
    Conjugué
    • 56
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Neuregulin 1 est non-conjugé
    Application
    • 89
    • 40
    • 39
    • 39
    • 37
    • 37
    • 24
    • 14
    • 12
    • 12
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    Synthesized peptide derived from Human NRG1 isoform-10.
    Isotype
    IgG
    Top Product
    Discover our top product NRG1 Anticorps primaire
  • Indications d'application
    WB:1:500-1:3000, IHC:1:50-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Neuregulin 1 (NRG1)
    Autre désignation
    NRG1 (NRG1 Produits)
    Synonymes
    anticorps 6030402G23Rik, anticorps ARIA, anticorps D230005F13Rik, anticorps GGF, anticorps GGFII, anticorps HRG, anticorps HRGalpha, anticorps Hgl, anticorps NDF, anticorps SMDF, anticorps GGF2, anticorps HGL, anticorps HRG1, anticorps HRGA, anticorps MST131, anticorps NRG-1, anticorps heregulin, anticorps nrg1-A, anticorps pro-neuregulin-1, anticorps NRG1, anticorps wu:fm70e01, anticorps DKFZp459A1838, anticorps neuregulin 1, anticorps histidine rich glycoprotein, anticorps neuregulin 1 L homeolog, anticorps Nrg1, anticorps NRG1, anticorps HRG, anticorps nrg1.L, anticorps nrg1
    Sujet

    Background: The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

    Xiao-Feng Le, Cancer Res., Jul 2000, 60: 3522 - 3531.
    Samuel D. H. Chan, J. Biol. Chem., Sep 1995, 270: 22608.
    Daniel C. Gamett, J. Biol. Chem., Aug 1995, 270: 19022.
    Mohammed Rahmatullah, Mol. Cell. Biol., Nov 1998, 18: 6245 - 6252.

    Aliases: Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, NRG1, GGF

    UniProt
    Q15491
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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