beta Synuclein anticorps
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- Antigène Voir toutes beta Synuclein (SNCB) Anticorps
- beta Synuclein (SNCB) (Synuclein, beta (SNCB))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp beta Synuclein est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from Human Synuclein beta antibody.
- Isotype
- IgG
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- Indications d'application
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- beta Synuclein (SNCB) (Synuclein, beta (SNCB))
- Autre désignation
- SNCB (SNCB Produits)
- Synonymes
- anticorps AI838531, anticorps betaSYN, anticorps zgc:66343, anticorps sncb, anticorps MGC75784, anticorps LOC619281, anticorps SNCB, anticorps syub, anticorps synuclein beta, anticorps synuclein, beta, anticorps synuclein beta L homeolog, anticorps Beta-synuclein, anticorps SNCB, anticorps Sncb, anticorps sncb, anticorps sncb.L, anticorps syub
- Sujet
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Background: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Yuxin Fan, Hum. Mol. Genet., Oct 2006, 15: 3002 - 3011.
Makoto Hashimoto, J. Biol. Chem., May 2004, 279: 23622 - 23629.
Cristine Alves da Costa, J. Biol. Chem., Sep 2003, 278: 37330 - 37335.
Heather Snyder, J. Biol. Chem., Mar 2005, 280: 7562 - 7569.Aliases: 14 kDa brain-specific protein antibody, Beta-synuclein antibody, Phosphoneuroprotein 14 antibody, PNP14 antibody, Sncb antibody, Synuclein beta antibody, SYUB_HUMAN antibody
- UniProt
- Q16143
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