CDH23 anticorps

N° du produit ABIN7183278

Détail du produit anti-CDH23 anticorps

Antigène: CDH23 (Cadherin 23 (CDH23))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDH23 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of Human CDH23.

Isotype: IgG

Information d'application

Indications d'application: IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CDH23

Antigène: CDH23 (Cadherin 23 (CDH23))

Autre désignation: CDH23 (CDH23 Produits)

Synonymes: anticorps 4930542A03Rik, anticorps USH1D, anticorps ahl, anticorps ahl1, anticorps bob, anticorps bus, anticorps mdfw, anticorps nmf112, anticorps nmf181, anticorps nmf252, anticorps sals, anticorps v, anticorps CDHR23, anticorps W, anticorps cadherin 23 (otocadherin), anticorps cadherin related 23, anticorps cadherin-related 23, anticorps Cdh23, anticorps CDH23

Sujet:

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

Bolz H., Nat. Genet. 27:108-112(2001).
Clark H.F., Genome Res. 13:2265-2270(2003).
Bork J.M., Am. J. Hum. Genet. 68:26-37(2001).

Aliases: CDH23 antibody, KIAA1774 antibody, KIAA1812 antibody, UNQ1894/PRO4340Cadherin-23 antibody, Otocadherin antibody

UniProt: Q9H251

Pathways: Sensory Perception of Sound