CIT anticorps

N° du produit ABIN7183401

Détail du produit anti-CIT anticorps

Antigène: CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIT est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of Human CTRO.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CIT

Antigène: CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

Autre désignation: CIT (CIT Produits)

Synonymes: anticorps CIT, anticorps crik, anticorps xcit, anticorps stk21, anticorps C030025P15Rik, anticorps CRIK, anticorps CRIK-SK, anticorps Cit-k, anticorps STK21, anticorps citron rho-interacting serine/threonine kinase, anticorps citron (rho-interacting, serine/threonine kinase 21), anticorps citron Rho-interacting kinase, anticorps citron, anticorps Cit, anticorps CIT, anticorps LOC100083347, anticorps cit

Sujet:

Background: Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.

Nagase T., DNA Res. 6:63-70(1999).
Scherer S.E., Nature 440:346-351(2006).
Gruneberg U., J. Cell Biol. 172:363-372(2006).

Aliases: CIT antibody, CRIK antibody, KIAA0949 antibody, STK21Citron Rho-interacting kinase antibody, CRIK antibody, EC 2.7.11.1 antibody, Serine/threonine-protein kinase 21 antibody

UniProt: O14578

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2