PDZD2 anticorps

N° du produit ABIN7183951

Détail du produit anti-PDZD2 anticorps

Antigène: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZD2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of Human PDZD2.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PDZD2

Antigène: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Autre désignation: PDZD2 (PDZD2 Produits)

Synonymes: anticorps AIPC, anticorps PAPIN, anticorps PDZK3, anticorps PIN1, anticorps 4930537L06Rik, anticorps A930022H17Rik, anticorps Gm82, anticorps Pdzk3, anticorps mKIAA0300, anticorps Papin, anticorps PDZ domain containing 2, anticorps PDZD2, anticorps Pdzd2

Sujet:

Background: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Chaib H., Cancer Res. 61:2390-2394(2001).
Nagase T., DNA Res. 4:141-150(1997).

Aliases: PDZD2 antibody, AIPC antibody, KIAA0300 antibody, PDZK3 antibody, PDZ domain-containing protein 2 antibody, Activated in prostate cancer protein antibody, PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2] antibody

UniProt: O15018