STK36 anticorps
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- Antigène Voir toutes STK36 Anticorps
- STK36 (serine/threonine Kinase 36 (STK36))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STK36 est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from internal of Human STK36.
- Isotype
- IgG
- Top Product
- Discover our top product STK36 Anticorps primaire
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- Indications d'application
- WB:1:500-1:3000, IHC:1:50-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- STK36 (serine/threonine Kinase 36 (STK36))
- Autre désignation
- STK36 (STK36 Produits)
- Synonymes
- anticorps FU, anticorps fused-like, anticorps 1700112N14Rik, anticorps B930045J24, anticorps Fused, anticorps mKIAA1278, anticorps fu, anticorps si:dkey-180i4.3, anticorps zgc:152944, anticorps serine/threonine kinase 36, anticorps serine/threonine kinase 36 (fused homolog, Drosophila), anticorps STK36, anticorps Stk36, anticorps stk36
- Sujet
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Background: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia.
Murone M., Nat. Cell Biol. 2:310-312(2000).
Nagase T., DNA Res. 6:337-345(1999).
Hillier L.W., Nature 434:724-731(2005).Aliases: FU antibody, Fused homolog antibody, KIAA1278 antibody, Serine/threonine kinase 36, fused homolog antibody, Serine/threonine protein kinase 36 fused homolog antibody, Serine/threonine-protein kinase 36 antibody, STK36 antibody, STK36_HUMAN antibody
- UniProt
- Q9NRP7
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