TSEN54 anticorps

N° du produit ABIN7184298

Détail du produit anti-TSEN54 anticorps

Antigène: TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSEN54 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of Human TSEN54.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TSEN54

Antigène: TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))

Autre désignation: TSEN54 (TSEN54 Produits)

Synonymes: anticorps zgc:109927, anticorps 0610034P02Rik, anticorps PCH2A, anticorps PCH4, anticorps SEN54L, anticorps sen54, anticorps tRNA splicing endonuclease subunit 54, anticorps TSEN54 tRNA splicing endonuclease subunit, anticorps tRNA splicing endonuclease 54 homolog (S. cerevisiae), anticorps TSEN54, anticorps tsen54, anticorps Tsen54

Sujet:

Background: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.

Zody M.C., Nature 440:1045-1049(2006).
Paushkin S.V., Cell 117:311-321(2004).
Ota T., Nat. Genet. 36:40-45(2004).

Aliases: HsSen54 antibody, PCH2A antibody, PCH4 antibody, sen54 antibody, SEN54 homolog antibody, SEN54_HUMAN antibody, SEN54L antibody, tRNA-intron endonuclease SEN54 antibody, tRNA-splicing endonuclease subunit SEN54 antibody, Tsen54 antibody, TSEN54 tRNA splicing endonuclease subunit antibody

UniProt: Q7Z6J9

Pathways: Synaptic Membrane