KLHL3 anticorps (N-Term)

N° du produit ABIN7184471

Détail du produit anti-KLHL3 anticorps

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from N-terminal of Human KLHL3.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KLHL3

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Autre désignation: KLHL3 (KLHL3 Produits)

Synonymes: anticorps 7530408C15Rik, anticorps AI430941, anticorps EG627648, anticorps PHA2D, anticorps RGD1565218, anticorps kelch like family member 3, anticorps kelch-like 3, anticorps kelch-like family member 3, anticorps KLHL3, anticorps Klhl3

Sujet:

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.

Lai F., Genomics 66:65-75(2000).
Hirosawa M., DNA Res. 6:329-336(1999).
Ota T., Nat. Genet. 36:40-45(2004).

Aliases: KLHL3 antibody, KIAA1129 antibody, Kelch-like protein 3 antibody

UniProt: Q9UH77