NKX3-1 anticorps (N-Term)

N° du produit ABIN7184486

Détail du produit anti-NKX3-1 anticorps

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from N-terminal of Human NKX3.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: NKX3-1 (NKX3-1 Produits)

Synonymes: anticorps Xbagpipe, anticorps Xbap, anticorps bagpipe, anticorps koza, anticorps nkx3-1, anticorps nkx3.1, anticorps si:ch211-67o1.2, anticorps nkx3a, anticorps MGC53041, anticorps MGC97890, anticorps Bax, anticorps NKX3.1, anticorps NKX3A, anticorps Nkx-3.1, anticorps BAPX2, anticorps NKX3, anticorps NK3 homeobox 1 L homeolog, anticorps NK3 homeobox 1, anticorps NK-3 transcription factor, locus 1 (Drosophila), anticorps nkx3-1.L, anticorps NKX3-1, anticorps nkx3-1, anticorps Nkx3-1

Sujet:

Background: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Cai Bowen, Cancer Res., Jan 2007, 67: 455 - 464.
Xiang Li, Mol. Cell. Biol., Apr 2006, 26: 3008 - 3017.
Ekatherine Asatiani, Cancer Res., Feb 2005, 65: 1164 - 1173.
Carlise R. Bethel, Cancer Res., Nov 2006, 66: 10683 - 10690.

Aliases: BAPX 2 antibody, BAPX2 antibody, Homeobox protein NK-3 homolog A antibody, Homeobox protein Nkx 3.1 antibody, Homeobox protein Nkx-3.1 antibody, Homeobox protein Nkx3.1 antibody, NK homeobox (Drosophila) family 3 A antibody, NK homeobox family 3 A antibody, NK homeobox, family 3, member A antibody, NK3 homeobox 1 antibody, NK3 transcription factor homolog A antibody, NK3 transcription factor related locus 1 antibody, NKX 3 antibody, Nkx 3.1 antibody, NKX 3A antibody, NKX3 1 antibody, NKX3 antibody, Nkx3-1 antibody, NKX3.1 antibody, Nkx3.1, mouse, homolog of antibody, NKX31_HUMAN antibody, NKX3A antibody

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus