FGF23 anticorps (AA 21-120)

N° du produit ABIN714461

Détail du produit anti-FGF23 anticorps

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Épitope: AA 21-120

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF23 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FGF23

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-FGF23 (ABIN714461)

Schumacher, Alampour-Rajabi, Ponomariov, Curaj, Wu, Staudt, Rusu, Jankowski, Marx, Jankowski, Brandenburg, Liehn, Schuh: "Cardiac FGF23: new insights into the role and function of FGF23 after acute myocardial infarction." dans: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 40, pp. 47-54, (2019) (PubMed).

Andersen, Huntley, Sandberg, Heublein, Burnett: "Elevation of circulating but not myocardial FGF23 in human acute decompensated heart failure." dans: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 31, Issue 5, pp. 767-72, (2016) (PubMed).

Détails sur FGF23

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Autre désignation: FGF23 (FGF23 Produits)

Synonymes: anticorps FGF23, anticorps ADHR, anticorps FGFN, anticorps HPDR2, anticorps HYPF, anticorps PHPTC, anticorps fibroblast growth factor 23, anticorps fgf23, anticorps FGF23, anticorps Fgf23

Sujet:

Synonyms: ADHR, FGFN, HYPF, HPDR2, PHPTC, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor, FGF23, UNQ327/PRO9828

Background: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

ID gène: 8074

UniProt: Q9GZV9

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion