PDGFC anticorps (AA 201-300)

N° du produit ABIN714566

Détail du produit anti-PDGFC anticorps

Antigène: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Épitope: AA 201-300

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDGFC/VEGF E

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PDGFC (ABIN714566)

Hurley, Adams, Wang, Jiang, Meo Burt, Du, Xiao: "Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2." dans: Journal of cellular biochemistry, (2015) (PubMed).

Détails sur PDGFC

Antigène: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Autre désignation: PDGF C (PDGFC Produits)

Synonymes: anticorps SCDGF, anticorps FALLOTEIN, anticorps 1110064L01Rik, anticorps AI647969, anticorps PDGF-C, anticorps platelet derived growth factor C, anticorps platelet-derived growth factor, C polypeptide, anticorps PDGFC, anticorps Pdgfc

Classe de substances: Viral Protein

Sujet:

Synonyms: SCDGF, FALLOTEIN, Platelet-derived growth factor C, PDGF-C, Spinal cord-derived growth factor, VEGF-E, PDGFC, UNQ174/PRO2

Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.

ID gène: 56034

UniProt: Q9NRA1

Pathways: Signalisation RTK, Platelet-derived growth Factor Receptor Signaling